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February 20, 2010 11:59:41
Posted By Lori @ GREYlong


Lymphoma is one of the most common and fatal cancers in dogs. Most dogs treated with chemotherapy go into remission, but the cancer quickly develops drug resistance and recurs. 

 

Chemotherapy generally works by initiating apoptosis, a normal process in which cells undergo programmed death. Apoptosis occurs throughout life and is critical for developing and maintaining healthy tissues. Cancer cells develop ways to avoid apoptosis, which allows them to grow and survive in an uncontrolled fashion.

 

Researchers will study a novel compound, PAC-1, that has been shown to induce apoptosis in tumor cells without the presence of chemotherapy. This study will evaluate safety and dosing, as well as efficacy, of PAC-1 in dogs with lymphoma. 

 

This compound holds great promise for the treatment of this disease, as well as other cancers.

 

 Morris Animal Foundation Study D09CA-082

www.morrisanimalfoundation.org

 

Your 2009 donations went to support this study!  Thank you,

 

University of Illinois letter
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January 16, 2010 09:53:35
Posted By Lori @ GREYlong
In 2009 the Food and Drug Administration (FDA) announced its approval of  the first canine cancer therapy in the US. The drug is called Palladiatm (toceranib phosphate) and it is used for treatment of skin based (mast cell) cancers in dogs. Read the report at www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm164118.htm
Pfizer is the manufacturer and hopes to make the product available to vets in 2010.  Palladia works by killing the tumor and cutting off its blood supply. 
Mast cells are produced in the bone marrow and normally occur in the skin. They are part of the immune system and contain histamine, which is released in response to  allergens or trauma. Mast cell tumors are a common skin tumor in dogs and cats, but can be found anywhere in the body.
According to the Morris Animal Foundation, after the age of 2, 1 in 2 dogs die of cancer. News of this treatment for skin cancer is encouraging to all dog owners!
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January 3, 2010 10:07:45
Posted By Lori @ GREYlong
We wish you a happy holiday and hope your new year is blessed with health and happiness.  We will be getting our year end newsletter out in January, but I did want to share some good news.
 

Morris Animal Foundation relayed some preliminary results on 1 of the studies we are actively supporting.  The study is being performed by Dr. Kisseberth at OSU.  They are investigating the genetic component of osteosarcoma, bone cancer.   They are using a tool called a canine microRNA micro array to determine the differences in the genetic express of healthy tissue and that of a tumor.  They are happy to report to us that the "preliminary data are encouraging."  So hoping that the scientists will soon be able to "map" this cancer and then focus on a specific treatment for bone cancer.  

may you and yours GREYlong!
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September 26, 2009 02:28:04
Posted By Lori @ GREYlong

It seems now days that we operate in a flurry. Everything is provided to keep us operating at a rapid pace – cell phones, PC’s, planes, schedules, and projects. When you think about it, the task you have to complete right now, . . . if you complete it, will it make a difference 30 minutes from now, 3 weeks from now, or 3 months from now?
 
Today I slowed down to think about this. A friend called. Her dog had been diagnosed with a squamous cell cancer. We were hopeful that surgery would cure it. But 3 weeks later, something was growing again on his head. She visited the vet to learn that the cancer was back, and most likely destroying the part of his skull to which it had been attached.
 
Flurry is a delightfully happy boy. He loves all. He loves his toys, his trips, his role in Becky’s life as her constant and faithful companion. But lately he hasn’t played with many toys.
 
So today, I ask you to pick your cause. Draw a line and say let’s put an end to _____. It can be poverty, environmental pollution, heath issues. It is your choice. As for me, for me, I will fill in the blank with the disease named cancer. 
 
Today, I ask you to support your cause – with your time and/or your resources. You can volunteer or you can save your pennies in a piggy bank for a year end donation.
 

But today, agree with me to not live in a flurry. But rather, Live as Flurry would. Enjoy your life, your simple pleasures. Accomplish those tasks that will make a difference 30 minutes from now, 3 weeks from now, and 3 months from now.

Flurry and Becky

 
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June 15, 2009 04:46:43
Posted By Lori @ GREYlong

3 on a bed

 

You know you are on vacation with your 4 legged friends when

 
1. You plan the time and location of your destination based on their likes for cool climates, and only dog friendly environments will do!
2. You pack a “doggy-all” bag with food, biscuits, vitamins, liver snacks, dental cleanser, dog bowls – all in all – the size of your own carry on bag!
3. The back of your car has more pillows and comforters than your hotel room.
4. You pack an ice chest with six or seven bottles of cold water and frozen ice packs, etc.
5. You check the AAA guide for only those hotels/motels that take dogs and you “redefine” the word small.
6. You will only lodge at a hotel that has 2 queen size or 1 king size bed – or you know some one will be sleeping on the floor and it won’t be a hound!
7. Your dog gets to eat diner on the bed, and you don’t!
8. You fall asleep with a dog paw cast carelessly across your chest
9. You stop at McD for breakfast, because you know your dog likes the scrambled eggs in their big breakfast.
10.          You ask your server for half a cup of hot water, because your dog likes their meals served warm.
11.          You carry out any leftover breakfast cereal milk to your car, because your dog  likes the milk.
 

You know you are at home – when the bed is all yours, the hounds are in theirs . . .

 
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